报告题目：Imaging of brain development: Pattern analysis
报告人：Prof. Hao Huang (the University of Pennsylvania)
报告人简介：Research in the Huang lab focuses on the structural and functional connectivity as well as macro- and micro-structural brain mapping using the latest noninvasive neuroimaging techniques. The research goal is to address the neuroscientific questions such as how the human brain functional networks emerge and what the structural and metabolic underpinnings of the brain networks are during development. Macro-structural brain mapping uses approaches of tractography and atlasing of the white matter tracts; micro-structural mapping uses the approaches of measuring neural structural properties at the level of micrometers by assessing diffusion properties of water molecules inside the brain. These quantifications are made possible with recent advancement of cutting-edge neuroimaging techniques, white matter tractography and big-data analytics of brain images.
Dr Huang is probably known best for initializing comprehensive brain mapping studies of developmental human brains during middle and late fetal stage, a critical development phase for CNS, using advanced diffusion MRI. The significance of this work is that it provides unprecedented neuroscientific knowledge on connectivity, anatomy and microstructure of early developing brains. The three research areas in the Huang lab is extended from this early work to delineate connectivity, create quantitative normal developmental brain charts and identify early biomarker in brains with psychiatric disorders. Dr Huang is the committee member of NIH-sponsored BrainSpan Consortium (
n.org). He has been the Ad Hoc member of various NIH Study Sections for multiple times. He is the Academic Editor of PLoS ONE and the leading guest editor of Frontiers in Neuroanatomy. He is the faculty director of Small Animal Imaging Facility (SAIF) at CHOP.